Endocrine Abstracts

Introduction: Methimazole is a widely prescribed antithyroid drug for the treatment of hyperthyroidism with a few adverse effects generally well-tolerated. However, methimazole-induced cholestatic jaundice (CJ) is a rare but serious adverse reaction. Herein we report a rare case of methimazole-induced CJ in a woman with hyperthyroidism.Case report: A 57-years-old women presented to our endocrinology department with a 2-week history of asthenia, insomnia,...

Introduction: Autoimmune polyglandular syndromes (APS) are rare polyendocrinopathies characterized by the failure of several endocrine glands as well as nonendocrine organs, caused by an immune-mediated destruction of endocrine tissues. The type IIIa APS is the association of thyroid autoimmune diseases, type 1 diabetes mellitus and other autoimmune conditions excluding Addison’s disease and hypoparathyroidism. Herein, we report the case of autoimmune hypothyroidism assoc...

Introduction: Acute adrenal insufficiency (AAI) is a rare but life-threatening condition. It may occur in 50 to 60% of septic shocks (SS). Its diagnosis can be difficult as symptoms are sometimes nonspecific. Herein, we report the case of a female patient with an AAI revealed during SS. A 30-year-old woman with a history of celiac disease since the age of 25 on a gluten-free diet, presented to the emergency department with abdominal pain, vomiting, fever and profound asthenia...

Introduction: Trisomy 21 is the most common chromosomal disorder. It is associated with an increased risk of endocrinopathy particularly thyroid gland disorders. This is frequently a compensated hypothyroidism. Hyperthyroidism is rare. We report the case of an adolescent with Down’s syndrome and celiac disease who presented with subclinical hyperthyroidism.Case report: It was a 15-year-old female from a non-consanguineous marriage with a history of ...